In the EC FP7 program HeCaToS, the group is responsible for physiological modelling of the liver and vertical integration of computational models which partly follow different mathematical formalisms. At the organ and the organism level, physiologically-based pharmacokinetic, short PBPK modelling is used to develop detailed descriptions of the liver including for example zonation.
Tiso GroupCopyright: iAMB
Research group Tiso exploits the natural metabolic variability of microorganisms for the synthesis of promising chemicals. The design of microbial cell factories is based on systems analysis of the underlying metabolic pathways. Using tools of modern synthetic biology metabolic engineering of microorganisms is carried out.